Title: Preliminary study of an automatic detection capsule system for gastric occult blood

Authors: Hongying Liu; Panpan Qiao; Xueli Wu; Lan Zhu; Xitian Pi; Xiaolin Zheng

Addresses: Key Laboratory of Biorheological Science and Technology of Ministry of Education, Bioengineering College, Chongqing University, Chongqing 400030, China ' Key Laboratory of Biorheological Science and Technology of Ministry of Education, Bioengineering College, Chongqing University, Chongqing 400030, China ' Key Laboratory of Biorheological Science and Technology of Ministry of Education, Bioengineering College, Chongqing University, Chongqing 400030, China ' Key Laboratory of Biorheological Science and Technology of Ministry of Education, Bioengineering College, Chongqing University, Chongqing 400030, China ' Key Laboratories for National Defense Science and Technology of Innovative Micro-Nano Devices and System Technology, Chongqing University, Chongqing 400030, China ' Key Laboratories for National Defense Science and Technology of Innovative Micro-Nano Devices and System Technology, Chongqing University, Chongqing 400030, China

Abstract: Based on capsule endoscopy and Occult Blood (OB) detection theory, an automatic detection capsule system for Gastric Occult Blood (GOB) was proposed. This system utilised the non-invasive deglutible capsule to automatically identify the GOB information and transmitted the detection result to the external device which could display the detection result and identify the OB status with a particular algorithm. Subjects or doctors could discriminate whether OB existed by observing the external device. This paper designed the automatic detection capsule of GOB and the detecting sensor based on collaurum immune theory. We did in vitro experiments to testify the system and acquired the detecting result image information. Experimental results indicated that the effective detection concentration range of the OB sensor was 6-1800 μg/ml. With simplicity and reliability, this system provides a new idea for the screening of early stage gastric cancer.

Keywords: automatic detection capsules; gastric occult blood; GOB; imaging sensors; wireless transmission; biomedical engineering; capsule endoscopy; occult blood detection; occult bleeding; collaurum immune theory; cancer screening; early stage gastric cancer; stomach cancer; smart capsules.

DOI: 10.1504/IJBET.2013.057925

International Journal of Biomedical Engineering and Technology, 2013 Vol.13 No.2, pp.105 - 116

Received: 15 Nov 2012
Accepted: 09 Sep 2013
Published online: 27 Sep 2014 *

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