Title: Nutrition and disease-related entropy generation in cancer

Authors: Melek Ece Öngel; Cennet Yildiz; Bayram Yilmaz; Mustafa Özilgen

Addresses: Department and Nutrition and Dietetics, Yeditepe University, 34755 Atasehir, Istanbul, Turkey ' Department of Food Engineering, Yeditepe University, 34755 Atasehir, Istanbul, Turkey ' Department of Physiology, Faculty of Medicine, Yeditepe University, 34755 Atasehir, Istanbul, Turkey ' Department of Food Engineering, Yeditepe University, 34755 Atasehir, Istanbul, Turkey

Abstract: The lifespan entropy generation limit concept suggests that living beings die after generating a definite amount of lifespan entropy, since their bodies cannot tolerate accumulating more damage. A healthy person, who has a lifespan of 78.6 years may generate 11,404 kJ/kg K of nutrition-related lifespan entropy. If that person should be diagnosed with cancer at the age of 40, he/she would have already generated 5,803 kJ/kg K of nutrition-related entropy and may generate 5,593 kJ/kg K of more entropy until dying. After the onset of the disease, approximately 97 kJ/kg K of entropy may be generated via nutrition-related metabolic activity in five years. In lung cancer, disease-related entropy generation is 191 fold of that of the diet-related entropy generation and this is nine folds in skin cancer. This study points out that a very high fraction of the lifespan entropy generated by the cancer patients is fueled not by diet, but by tissue-scavenging, slowing down the scavenging-related chemical activity may actually increase the lifespan of the patients.

Keywords: cancer patients; tissue-scavenging; entropic-age; nutrition-related entropy generation; disease-related entropy generation.

DOI: 10.1504/IJEX.2021.114091

International Journal of Exergy, 2021 Vol.34 No.4, pp.411 - 423

Received: 16 Jul 2020
Accepted: 13 Aug 2020
Published online: 08 Apr 2021 *

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