Title: Protective effect of nano-electrostatic composite material on miners' skin and its influence on working state

Authors: Shuicheng Tian; Ying Chen; Yuan Zou

Addresses: School of Resources Engineering, Xi'an University of Architecture and Technology, Xi'an Shaanxi, 710055, China; College of Safety Science and Engineering, Xi'an University of Science and Technology, Xi'an Shaanxi, 710054, China ' School of Resources Engineering, Xi'an University of Architecture and Technology, Xi'an Shaanxi, 710055, China; College of Safety Science and Engineering, Xi'an University of Science and Technology, Xi'an Shaanxi, 710054, China ' Shaanxi Linbei Coal Mine, Liangting Town, Linyou County, Baoji Shaanxi 721505, China

Abstract: A nano-electrostatic composite material is proposed to promote the rapid healing of miners' skin injuries and maintain their good working state in the harsh underground environment. The poly (lactic-co-glycolic acid) (PLGA) nanoparticle therapy has a strong effect on maintaining the biological stability of the drug, so it is undertaken as a carrier to load the basic fibroblast growth factor (bFGF) into PLGA. The electrospinning technology is adopted to form a nano-electrospinning composite material (NECM), which is obviously interwoven into a network with uniform thickness. Sixty miners with skin injuries are treated with different dressings. It is found after 10 days that the wound healing rate of miners using NECM reaches 86.67%, which is much higher in contrast to that of the traditional medical dressings (43.3%). The main reason is that bFGF can promote the proliferation of wound granulation tissue, and loading it into nanofibre dressings can increase its bioavailability and promote the wound healing. Therefore, the application of bFGF/PLGA NECM has a significant effect on promoting the healing of miners' skin injuries, so it plays an important role in alleviating the psychological pressure of miners and enhancing their enthusiasm for work.

Keywords: nano-electrospinning composite material; skin protection; miner; working state.

DOI: 10.1504/IJNT.2022.128940

International Journal of Nanotechnology, 2022 Vol.19 No.6/7/8/9/10/11, pp.458 - 469

Received: 26 Nov 2020
Accepted: 29 Mar 2021
Published online: 13 Feb 2023 *

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