Title: Optimised deep neural network for cancer disease prediction using a genetic algorithm

Authors: Wasiur Rhmann

Addresses: School of Computer Application, Lovely Professional University, Punjab, 144402, India

Abstract: Detection of cancer at an early stage is a crucial activity for the oncologist for proper treatment of the disease. Various machine learning techniques are applied to detect different types of cancers. However, till date, the low accuracy in cancer detection is observed because limited focus has been given to addressing the dataset imbalance problem for cancer detection. In the present work, a novel genetic algorithm-based deep neural network (GA-DNN) is proposed to effectively detect the two types of cancers i.e., prostate cancer and breast cancer. Results obtained by GA-DNN are compared with support vector machine (SVM), random forest, and deep neural network (DNN). Best results are reported by GA-DNN for prostate cancer and breast cancer Coimbra datasets. It was observed that the optimised DNN gave the best results when the dataset is large.

Keywords: genetic algorithm; deep learning; hyper-parameter; disease datasets; cancer; prediction; machine learning.

DOI: 10.1504/IJBRA.2022.129262

International Journal of Bioinformatics Research and Applications, 2022 Vol.18 No.6, pp.578 - 595

Received: 11 Aug 2022
Accepted: 04 Jan 2023

Published online: 01 Mar 2023 *

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