Title: A novel Burkholderia vietnamiensis strain for biodegradation of residual tylosin antibiotic in fermentation solid waste

Authors: Yu-Long Ma; Yan Wang; Rui-Zhu Sun

Addresses: State Key Laboratory Cultivation Base of Energy Sources and Chemical Engineering, Ningxia University, Helanshan Rd. 539, Yinchuan 750021, China ' College of Chemistry and Chemical Engineering, Ningxia University, Helanshan Rd. 539, Yinchuan 750021, China ' College of Chemistry and Chemical Engineering, Ningxia University, Helanshan Rd. 539, Yinchuan 750021, China

Abstract: A large amount of fermentation solid waste (FSW) has been generated during the course of tylosin production. This FSW is difficult to be treated and reused because of tylosin residue. In this study, a novel strain TS1 was isolated and identified as Burkholderia vietnamiensis. This isolate exhibited a strong ability to degrade tylosin, and almost 100% of 200 mg kg⁻¹ tylosin was biodegraded after seven days of incubation. Medium pH and temperature had some influences on the biodegradation capacity of strain TS1. The favourable biodegrading conditions were at pH 7.0 and 30-35°C. The behaviour of tylosin degradation followed a first-order kinetic, and the half-lives were 1.54 to 1.70 days when the initial concentrations of tylosin were from 50 mg kg⁻¹ to 400 mg kg⁻¹. These findings suggest that strain TS1 can effectively degrade tylosin residue in FSW and may be used for biotreatment of antibiotic solid waste containing tylosin residue.

Keywords: antibiotic residue; biodegradation; Burkholderia vietnamiensis; biodegradation; tylosin residue; tylosin antibiotic; fermentation solid waste; half-life; identification; kinetics; solid waste management; biotreatment.

DOI: 10.1504/IJEWM.2015.073030

International Journal of Environment and Waste Management, 2015 Vol.16 No.3, pp.221 - 233

Received: 22 Sep 2014
Accepted: 18 Jul 2015
Published online: 12 Nov 2015 *

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