Botulinum neurotoxins are a unique group of proteins, with extreme biological activities in areas such as toxins, therapeutics and cosmetics. Clostridium botulinum has become a source of bioterror and beauty, both being pursued simultaneously for scientific development to counter the former while promoting the latter. TBJ provides an international forum and authoritative source of information encompassing varied fields, including microbiology, biochemistry, biophysics, biotechnology, proteomics, genomics, pharmacology, toxicology, drug development related to different forms/types of botulinum neurotoxins, and also Clostridium botulinum.
Topics covered include
Origin and microbiology
Genomics and structure
Mode of action
Biochemistry and host response
The botulism disease and treatment, incl. case studies/epidemiology
Diagnostics
Botulinum as a weapon and protection
Characterisation and antidote developments
Basis of therapeutic uses of botulinum
Diseases under treatment
Research on currently available pharmaceutical products
The objectives of TBJ are to disseminate knowledge, to provide a learned reference in the field, and to establish channels of communication amongst academics, medical and public health research experts, the pharmaceutical industry, the cosmetics industry, policy makers, and executives in industry, commerce and investment institutions. TBJ provides a forum to exchange scholarly ideas relevant to health, science, application and regulatory issues related to the botulinum neurotoxin and Clostridium botulinum.
Readership
Professionals in medicine, the pharmaceutical industry and the cosmetics industry
Academics involved and interested in teaching and research in the fundamental as well as applied aspects of botulinum and Clostridium botulinum
Government researchers involved in developing countermeasures against botulinum threat, and involved in safe use of botulinum as therapeutics
Industry researchers interested in developing new products based on botulinum neurotoxin
Policy makers involved in biodefense, homeland security, public safety, and regulatory compliance
General public interested in the use of botulinum-based pharmaceuticals and cosmeceuticals
Contents
TBJ publishes original and review papers, commentaries, technical reports, analytical models, mathematical simulations, case studies, conference reports, book reviews, notes, managerial and policy issues and news. Contributions may be by submission or invitation, and suggestions for Special Issues and publications are welcome.
Anniballi, Fabrizio, Istituto Superiore di Sanità, Italy (fabrizio.anniballiiss.it)
Editorial Board Member
Moore, Austen Peter, The Walton Centre for Neurology and Neurosurgery NHS Trust, UK
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