Plaque rupture in stenotic coronary artery model: a numerical study Online publication date: Thu, 29-Feb-2024
by Md. Rakibuzzaman; Hyoung-Ho Kim; Sang-Ho Suh; A.K.M. Parvez Iqbal; Byoung-Kwon Lee; Hyuck Moon Kwon
International Journal of Biomedical Engineering and Technology (IJBET), Vol. 44, No. 2, 2024
Abstract: Atherosclerosis is a type of cardiovascular disease in which a wounded endothelial cell triggers a series of biochemical responses to repair the damage. As a mechanical response to the arterial wall, wall-shear-stress (WSS) is well investigated to become a significant contributing factor for atherogenesis and the development of atherosclerosis. This vascular wall behaviour could be utilised to predict plaque biomechanical instability and rupture susceptibility. Plaque has a significant function in causing blood vessel ruptures. This study used fluid-structure interaction (FSI) which is the combination of finite volume method (FVM) and finite element method (FEM) to investigate the deformable structure during internal fluid flow. Therefore, this particular approach has been implemented to investigate the features of stenosed with and without plaque ruptures under various situations. The von Misses stress (VMS) and WSS were determined. Results revealed that on both sides of arterial branch, higher WSS took place than below the plaque. Moreover, the highest intensity of VMS was roughly equivalent, when the distance between the plaque and the inner wall of the vessel was less than 65 μm, but the greater the distance, the greater the stress.
Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Biomedical Engineering and Technology (IJBET):
Login with your Inderscience username and password:
Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.
If you still need assistance, please email subs@inderscience.com