A review of support vector machine in cancer prediction on genomic data Online publication date: Wed, 29-May-2024
by L. Revathi; Ramaswami Murugesh
International Journal of Bioinformatics Research and Applications (IJBRA), Vol. 20, No. 2, 2024
Abstract: Cancer is the most prevalent disease that leads to death globally. According to the World Health Organization (WHO) report, cancer claims over 10 million lives yearly. Extensive research has focused on early detection and prevention through clinical and laboratory studies. Genomic technologies enable the analysis of large cancer-related datasets, while machine learning algorithms aid in early detection. This paper explores earlier studies on supervised machine learning techniques and feature selection methods on high-dimensional gene expression data. Furthermore, this study emphasises the significance of support vector machine (SVM) in cancer prediction and diagnosis, highlighting its superior performance compared to other classification methods and in particular, the choice of kernel function strongly influences the performance of SVM. Additionally, feature selection extracts informative genes from microarray data which leads to high predictive accuracy and less computational complexity. The paper concludes that both machine learning approaches and SVM make substantial contributions to cancer prediction.
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