Discovering maximal size coherent biclusters from gene expression data Online publication date: Sat, 28-Mar-2015
by J. Bagyamani, K. Thangavel
International Journal of Healthcare Technology and Management (IJHTM), Vol. 12, No. 5/6, 2011
Abstract: Microarray experiments produce enormous amounts of data, leading to new requirements and challenges in bioinformatics. One of the major challenges in the analysis of such data sets is to discover local structures composed by sets of genes that show coherent expression patterns across subsets of experimental conditions. These patterns may provide clues about the main biological processes associated with different physiological states. This proposed algorithm includes gene selection and extraction of biclusters from gene expression data using difference matrix. This improved algorithm extracts biclusters with maximum volume that may be left unidentified.
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